ABSTRACT
Background: To date, the medical resources and the important clinical risk factors of non-severe patients with the 2019 coronavirus disease (COVID-19) have not been investigated.Methods: we retrospectively analyszed 104 patients with COVID-19 admitted to the isolation ward in Hubei, China, from February to March 2020. The general information, clinical symptoms, blood test and CT imaging characteristics were analyzed. Results: The median length of stay (LOS) is 14 days, and the cost of hospitalization (COH) is ＄2,522.86. The main influencing factors include the following：① CT imaging: lesions of the lungs were bilateral and multiple. The range of involved and interstitial changes affect the medical burden significantly (P=0.009 and P=0.013, respectively); ②Treatments: Patients were more severe with high flow nasal cannula oxygen therapy (HFNC) or used methylprednisolone more than 1mg / kg; ③ Blood test indicators: lymphocyte (LC) count level <1,000 and increased LDH (Lactate dehydrogenase) level have impact on medical burden; ④ These indicators have significant impact on medical resource after regression analysis except for LDH.Conclusions: The hospitalization cost of non-severe COVID-19 is higher than that of the common CAP patients. The main influencing factors are multiple extensive interstitial changes on CT scans, absolute lymphocyte level <1,000, use of high-dose methylprednisolone and HFNC.